Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel.

Bisphenol A (BPA) has attracted considerable public attention as it leaches from plastic used in food containers, is detectable in human fluids and recent epidemiologic studies link BPA exposure with diseases including cardiovascular disorders. As heart-toxicity may derive from modified cardiac elec...

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Bibliographic Details
Main Authors: Andrias O O'Reilly, Esther Eberhardt, Christian Weidner, Christian Alzheimer, B A Wallace, Angelika Lampert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407203?pdf=render