Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection.

Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection.

The E2 glycoprotein of Hepatitis C virus (HCV) is a major target of the neutralizing antibody (NAb) response with the majority of epitopes located within its receptor binding domain (RBD; 384-661). Within E2 are three variable regions located at the N-terminus (HVR1; 384-411), and internally at 460-...

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Bibliographic Details
Main Authors: Yousef M O Alhammad, Sanvir Maharajh, Rebecca Butcher, John-Sebastian Eden, Peter A White, Pantelis Poumbourios, Heidi E Drummer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4430534?pdf=render

Internet

http://europepmc.org/articles/PMC4430534?pdf=render

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