Candida albicans induces Metabolic Reprogramming in human NK cells and responds to Perforin with a Zinc Depletion Response

Candida albicans induces Metabolic Reprogramming in human NK cells and responds to Perforin with a Zinc Depletion Response

As part of the innate immune system, natural killer (NK) cells are directly involved in the response to fungal infections. Perforin has been identified as the major effector molecule acting against many fungal pathogens. While several studies have shown that perforin mediated fungicidal effects can...

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Bibliographic Details
Main Authors: Daniela eHellwig, Jessica eVoigt, Maria eBouzani, Jürgen eLöffler, Daniela eAlbrecht-Eckardt, Michael eWeber, Sascha eBrunke, Ronny eMartin, Oliver eKurzai, Kerstin eHünniger
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Microbiology
Subjects:
Candida albicans
Glycolysis
Perforin
Zinc
NK cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00750/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00750/full

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