Mechanisms of mono- and poly-ubiquitination: Ubiquitination specificity depends on compatibility between the E2 catalytic core and amino acid residues proximal to the lysine

<p>Abstract</p> <p>Ubiquitination involves the attachment of ubiquitin to lysine residues on substrate proteins or itself, which can result in protein monoubiquitination or polyubiquitination. Ubiquitin attachment to different lysine residues can generate diverse substrate-ubiquiti...

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Bibliographic Details
Main Authors: Sadowski Martin, Sarcevic Boris
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/5/1/19