The novel mouse mutant, <it>chuzhoi</it>, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

The novel mouse mutant, <it>chuzhoi</it>, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

<p>Abstract</p> <p>Background</p> <p>The planar cell polarity (PCP) signalling pathway is fundamental to a number of key developmental events, including initiation of neural tube closure. Disruption of the PCP pathway causes the severe neural tube defect of craniorachis...

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Bibliographic Details
Main Authors: Paudyal Anju, Damrau Christine, Patterson Victoria L, Ermakov Alexander, Formstone Caroline, Lalanne Zuzanna, Wells Sara, Lu Xiaowei, Norris Dominic P, Dean Charlotte H, Henderson Deborah J, Murdoch Jennifer N
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/10/87

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http://www.biomedcentral.com/1471-213X/10/87

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