Novel BRAF Alteration in a Sporadic Pilocytic Astrocytoma

Pilocytic astrocytoma (PA) is the most frequently encountered glial tumor (glioma or astrocytoma) in children. Recent studies have identified alterations in the BRAF serine/threonine kinase gene as the likely causative mutation in these childhood brain tumors. The majority of these genetic changes i...

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Bibliographic Details
Main Authors: Sonika Dahiya, Jinsheng Yu, Aparna Kaul, Jeffrey R. Leonard, David H. Gutmann
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/418672