Novel BRAF Alteration in a Sporadic Pilocytic Astrocytoma
Pilocytic astrocytoma (PA) is the most frequently encountered glial tumor (glioma or astrocytoma) in children. Recent studies have identified alterations in the BRAF serine/threonine kinase gene as the likely causative mutation in these childhood brain tumors. The majority of these genetic changes i...
Main Authors: | Sonika Dahiya, Jinsheng Yu, Aparna Kaul, Jeffrey R. Leonard, David H. Gutmann |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2012/418672 |
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