MicroRNA-16 targets mRNA involved in neurite extension and branching in hippocampal neurons during presymptomatic prion disease

The mechanisms that lead to neuronal death in neurodegenerative diseases are poorly understood. Prion diseases, like many more common disorders such as Alzheimer's and Parkinson's diseases, are characterized by the progressive accumulation of misfolded disease-specific proteins. The earlie...

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Bibliographic Details
Main Authors: Kristyn Burak, Lise Lamoureux, Amrit Boese, Anna Majer, Reuben Saba, Yulian Niu, Kathy Frost, Stephanie A. Booth
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117302978