Role of germination in murine airway CD8+ T-cell responses to Aspergillus conidia.

Pulmonary exposure to Aspergillus fumigatus has been associated with morbidity and mortality, particularly in immunocompromised individuals. A. fumigatus conidia produce β-glucan, proteases, and other immunostimulatory factors upon germination. Murine models have shown that the ability of A. fumigat...

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Bibliographic Details
Main Authors: Steven P Templeton, Amanda D Buskirk, Brandon Law, Brett J Green, Donald H Beezhold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3076443?pdf=render