Genetic association mapping via evolution-based clustering of haplotypes.
Multilocus analysis of single nucleotide polymorphism haplotypes is a promising approach to dissecting the genetic basis of complex diseases. We propose a coalescent-based model for association mapping that potentially increases the power to detect disease-susceptibility variants in genetic associat...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-07-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1913101?pdf=render |