Integrating germline and somatic variation information using genomic data for the discovery of biomarkers in prostate cancer

Abstract Background Prostate cancer (PCa) is the most common diagnosed malignancy and the second leading cause of cancer-related deaths among men in the United States. High-throughput genotyping has enabled discovery of germline genetic susceptibility variants (herein referred to as germline mutatio...

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Bibliographic Details
Main Authors: Tarun Karthik Kumar Mamidi, Jiande Wu, Chindo Hicks
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-019-5440-8