Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype.

Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype.

Tumor heterogeneity is a major obstacle for finding effective treatment of Glioblastoma (GBM). Based on global expression analysis, GBM can be classified into distinct subtypes: Proneural, Neural, Classical and Mesenchymal. The signatures of these different tumor subtypes may reflect the phenotypes...

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Bibliographic Details
Main Authors: Liang Lei, Adam M Sonabend, Paolo Guarnieri, Craig Soderquist, Thomas Ludwig, Steven Rosenfeld, Jeffrey N Bruce, Peter Canoll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3100315?pdf=render

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http://europepmc.org/articles/PMC3100315?pdf=render

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