CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production.

The facultative intracellular bacterium Listeria monocytogenes (Lm) may cause severe infection in humans and livestock. Control of acute listeriosis is primarily dependent on innate immune responses, which are strongly regulated by NF-κB, and tissue protective factors including fibrin. However, mole...

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Bibliographic Details
Main Authors: Gopala Nishanth, Martina Deckert, Katharina Wex, Ramin Massoumi, Katrin Schweitzer, Michael Naumann, Dirk Schlüter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3695090?pdf=render