Traumatic Brain Injury by Weight-Drop Method Causes Transient Amyloid-β Deposition and Acute Cognitive Deficits in Mice

There has been growing awareness of the correlation between an episode of traumatic brain injury (TBI) and the development of Alzheimer’s disease (AD) later in life. It has been reported that TBI accelerated amyloid-β (Aβ) pathology and cognitive decline in the several lines of AD model mice. Howeve...

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Bibliographic Details
Main Authors: Hajime Shishido, Masaki Ueno, Kana Sato, Masahisa Matsumura, Yasunori Toyota, Yutaka Kirino, Takashi Tamiya, Nobuyuki Kawai, Yasushi Kishimoto
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2019/3248519