An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo

An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo

The authors have previously reported split-GFP-based contact site sensors (SPLICS) to document endoplasmic reticulum/mitochondria contact sites. Here they extend this work and develop a range of improved SPLICS sensors to detect single and multiple organelle contact sites at different distances.

Bibliographic Details
Main Authors: Francesca Vallese, Cristina Catoni, Domenico Cieri, Lucia Barazzuol, Omar Ramirez, Valentina Calore, Massimo Bonora, Flavia Giamogante, Paolo Pinton, Marisa Brini, Tito Calì
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19892-6

Internet

https://doi.org/10.1038/s41467-020-19892-6

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