An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo
The authors have previously reported split-GFP-based contact site sensors (SPLICS) to document endoplasmic reticulum/mitochondria contact sites. Here they extend this work and develop a range of improved SPLICS sensors to detect single and multiple organelle contact sites at different distances.
Bibliographic Details
Main Authors: |
Francesca Vallese,
Cristina Catoni,
Domenico Cieri,
Lucia Barazzuol,
Omar Ramirez,
Valentina Calore,
Massimo Bonora,
Flavia Giamogante,
Paolo Pinton,
Marisa Brini,
Tito Calì |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2020-11-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-020-19892-6
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