Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

At least 15 cases of human beings infected with H5N6 have been reported since 2014, of which at least nine were fatal. The highly pathogenic avian H5N6 influenza virus may pose a serious threat to both public health and the poultry industry. However, the molecular features promoting the adaptation o...

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Bibliographic Details
Main Authors: Chunmao Zhang, Zongzheng Zhao, Zhendong Guo, Jiajie Zhang, Jiaming Li, Yifei Yang, Shaoxia Lu, Zhongyi Wang, Min Zhi, Yingying Fu, Xiaoyu Yang, Lina Liu, Yi Zhang, Yuping Hua, Linna Liu, Hongliang Chai, Jun Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Microbiology
Subjects:
avian H5N6 influenza A virus
amino acid substitutions
mammalian adaptation
pathogenicity
transmissibility
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01763/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01763/full

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