Automated classification and characterization of the mitotic spindle following knockdown of a mitosis-related protein

Abstract Background Cell division (mitosis) results in the equal segregation of chromosomes between two daughter cells. The mitotic spindle plays a pivotal role in chromosome alignment and segregation during metaphase and anaphase. Structural or functional errors of this spindle can cause aneuploidy...

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Bibliographic Details
Main Authors: Matloob Khushi, Imraan M. Dean, Erdahl T. Teber, Megan Chircop, Jonathan W. Arthur, Neftali Flores-Rodriguez
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1966-4