Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease.

Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease.

BACKGROUND:The variable course of autosomal dominant polycystic kidney disease (ADPKD), and the advent of renoprotective treatment require early risk stratification. We applied urinary metabolomics to explore differences associated with estimated glomerular filtration rate (eGFR; CKD-EPI equation) a...

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Bibliographic Details
Main Authors: Shosha E I Dekker, Aswin Verhoeven, Darius Soonawala, Dorien J M Peters, Johan W de Fijter, Oleg A Mayboroda, DIPAK Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233213

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https://doi.org/10.1371/journal.pone.0233213

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