Histone Modifying Enzymes in Gynaecological Cancers

Genetic and epigenetic factors contribute to the development of cancer. Epigenetic dysregulation is common in gynaecological cancers and includes altered methylation at CpG islands in gene promoter regions, global demethylation that leads to genome instability and histone modifications. Histones are...

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Bibliographic Details
Main Authors: Priya Ramarao-Milne, Olga Kondrashova, Sinead Barry, John D. Hooper, Jason S. Lee, Nicola Waddell
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/4/816