Aminoglucose-functionalized, redox-responsive polymer nanomicelles for overcoming chemoresistance in lung cancer cells

Aminoglucose-functionalized, redox-responsive polymer nanomicelles for overcoming chemoresistance in lung cancer cells

Abstract Background Chemotherapeutic drugs used for cancer therapy frequently encounter multiple-drug resistance (MDR). Nanoscale carriers that can target tumors to accumulate and release drugs intracellularly have the greatest potential for overcoming MDR. Glucose transporter-1 (GLUT-1) and glutath...

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Bibliographic Details
Main Authors: Yi Zhou, Huaying Wen, Liang Gu, Jijun Fu, Jiayi Guo, Lingran Du, Xiaoqin Zhou, Xiyong Yu, Yugang Huang, He Wang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Nanobiotechnology
Subjects:
Gult-1
Redox-responsive polymer
Nanomicelles
Multidrug resistance
Cancer therapy
Online Access:http://link.springer.com/article/10.1186/s12951-017-0316-z

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http://link.springer.com/article/10.1186/s12951-017-0316-z

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