CD133/prominin-1-mediated autophagy and glucose uptake beneficial for hepatoma cell survival.

CD133/Prominin-1 is a pentaspan transmembrane protein that has been frequently used as a biomarker for cancer stem cells, although its biological function is unclear. The aim of our study was to explore the intrinsic functions of CD133 membrane protein in hepatoma cells during autophagy, apoptosis,...

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Bibliographic Details
Main Authors: Haiyang Chen, Zaili Luo, Liwei Dong, Yexiong Tan, Jiamei Yang, Gensheng Feng, Mengchao Wu, Zhong Li, Hongyang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577658?pdf=render