The Identification of Plasma Exosomal miR-423-3p as a Potential Predictive Biomarker for Prostate Cancer Castration-Resistance Development by Plasma Exosomal miRNA Sequencing

The Identification of Plasma Exosomal miR-423-3p as a Potential Predictive Biomarker for Prostate Cancer Castration-Resistance Development by Plasma Exosomal miRNA Sequencing

Castration-resistant prostate cancer (CRPC) is the major cause of death from prostate cancer. Biomarkers to improve early detection and prediction of CRPC especially using non-invasive liquid biopsies could improve outcomes. Therefore, we investigated the plasma exosomal miRNAs associated with CRPC...

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Bibliographic Details
Main Authors: Tianyu Guo, Yang Wang, Jing Jia, Xueying Mao, Elzbieta Stankiewicz, Glenda Scandura, Edwina Burke, Lei Xu, Jacek Marzec, Caitlin R. Davies, Jiaying Jasmin Lu, Prabhakar Rajan, Alistair Grey, Karen Tipples, John Hines, Sakunthala Kudahetti, Tim Oliver, Thomas Powles, Constantine Alifrangis, Manish Kohli, Greg Shaw, Wen Wang, Ninghan Feng, Jonathan Shamash, Daniel Berney, Liang Wang, Yong-Jie Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
prostate cancer
castration-resistance development
biomarker
plasma exosome miRNA
miR-423-3p
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.602493/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.602493/full

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