Synthesis, Docking Study and β-Adrenoceptor Activity of Some New Oxime Ether Derivatives

A new series of oxime ethers 4a–z was designed and synthesized to test the blocking activity against β1 and β2-adrenergic receptors. Docking of these ether derivatives into the active site of the identified 3D structures of β1 and β2-adrenergic receptors showed MolDock scores comparable to those of...

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Bibliographic Details
Main Authors: Hazem A. Ghabbour, Eman R. El-Bendary, Mahmoud B. El-Ashmawy, Mohamed M. El-Kerdawy
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/3/3417