Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination

Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination

Abstract Over recent years, human autoantibodies targeting myelin oligodendrocyte glycoprotein (MOG Ab) have been associated with monophasic and relapsing central nervous system demyelination involving the optic nerves, spinal cord, and brain. While the clinical relevance of MOG Ab detection is beco...

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Bibliographic Details
Main Authors: Fiona Tea, Joseph A. Lopez, Sudarshini Ramanathan, Vera Merheb, Fiona X. Z. Lee, Alicia Zou, Deepti Pilli, Ellis Patrick, Anneke van der Walt, Mastura Monif, Esther M. Tantsis, Eppie M. Yiu, Steve Vucic, Andrew P. D. Henderson, Anthony Fok, Clare L. Fraser, Jeanette Lechner-Scott, Stephen W. Reddel, Simon Broadley, Michael H. Barnett, David A. Brown, Jan D. Lunemann, Russell C. Dale, Fabienne Brilot, the Australasian and New Zealand MOG Study Group
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Acta Neuropathologica Communications
Subjects:
Myelin oligodendrocyte glycoprotein
Antibody
Epitope, antigen conformation
Optic neuritis
Multiple sclerosis
Diagnosis
Online Access:http://link.springer.com/article/10.1186/s40478-019-0786-3

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http://link.springer.com/article/10.1186/s40478-019-0786-3

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