Read-SpaM: assembly-free and alignment-free comparison of bacterial genomes with low sequencing coverage

Abstract Background In many fields of biomedical research, it is important to estimate phylogenetic distances between taxa based on low-coverage sequencing reads. Major applications are, for example, phylogeny reconstruction, species identification from small sequencing samples, or bacterial strain...

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Bibliographic Details
Main Authors: Anna-Katharina Lau, Svenja Dörrer, Chris-André Leimeister, Christoph Bleidorn, Burkhard Morgenstern
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3205-7