Reinstatement of Morphine-Induced Conditioned Place Preference in Mice by Priming Injections

To construct a model of relapse of drug abuse in mice, the induction, we evaluated the extinction and reinstatement of morphine-induced place preference. In Experiment 1, we examined the effects of morphine (0, 2, 3, 5, 10, 20 and 40 mg/kg) in the conditioned place preference (CPP) paradigm. Mice sh...

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Bibliographic Details
Main Authors: B. Ribeiro Do Couto, M. A. Aguilar, C. Manzanedo, M. Rodríguez-Arias, J. Miñarro
Format: Article
Language:English
Published: Hindawi Limited 2003-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/NP.2003.279