Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import

<p>Abstract</p> <p>Background</p> <p>In addition to mediating the integration process, HIV-1 integrase (IN) has also been implicated in different steps during viral life cycle including reverse transcription and viral DNA nuclear import. Although the karyophilic propert...

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Bibliographic Details
Main Authors: Fowke Keith R, Ao Zhujun, Cohen Éric A, Yao Xiaojian
Format: Article
Language:English
Published: BMC 2005-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/62