Endogenous morphine levels are increased in sepsis: a partial implication of neutrophils.

Endogenous morphine levels are increased in sepsis: a partial implication of neutrophils.

BACKGROUND: Mammalian cells synthesize morphine and the respective biosynthetic pathway has been elucidated. Human neutrophils release this alkaloid into the media after exposure to morphine precursors. However, the exact role of endogenous morphine in inflammatory processes remains unclear. We post...

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Bibliographic Details
Main Authors: Elise Glattard, Ingeborg D Welters, Thomas Lavaux, Arnaud H Muller, Alexis Laux, Dan Zhang, Alexander R Schmidt, François Delalande, Benoît-Joseph Laventie, Sylvie Dirrig-Grosch, Didier A Colin, Alain Van Dorsselaer, Dominique Aunis, Marie-Hélène Metz-Boutigue, Francis Schneider, Yannick Goumon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2808358?pdf=render

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http://europepmc.org/articles/PMC2808358?pdf=render

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