Amino functionalized chiral mesoporous silica nanoparticles for improved loading and release of poorly water-soluble drug

In the present paper, chiral mesoporous silica nano-cocoon (A-CMSN) functionalized with amino group was synthesized, and its loading and release of indomethacin (IMC), a poorly soluble drug, was studied. Due to the use of chiral anionic surfactants as a template, A-CMSN possessed 2D hexagonal nano-c...

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Bibliographic Details
Main Authors: Xin Wang, Chang Li, Na Fan, Jing Li, Haotian Zhang, Lei Shang, Zhonggui He, Jin Sun
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Asian Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618301041