Changes in pulmonary endothelial cell properties during bleomycin-induced pulmonary fibrosis

Changes in pulmonary endothelial cell properties during bleomycin-induced pulmonary fibrosis

Abstract Background Pulmonary fibrosis is a progressive and lethal disease characterized by damage to the lung parenchyma with excess extracellular matrix deposition. The involvement of endothelial cells in fibrosis development is unclear. Methods We isolated pulmonary endothelial cells, using a mag...

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Bibliographic Details
Main Authors: Shinpei Kato, Naoki Inui, Akio Hakamata, Yuzo Suzuki, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Hiroshi Watanabe, Takafumi Suda
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Respiratory Research
Subjects:
α-SMA
Bleomycin
Endothelial cell
Fibrosis
Nitric oxide
Prostaglandin I2
Online Access:http://link.springer.com/article/10.1186/s12931-018-0831-y

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http://link.springer.com/article/10.1186/s12931-018-0831-y

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