Mechanism-based design of 2,3-benzodiazepine inhibitors for AMPA receptors
2,3-Benzodiazepine (2,3-BDZ) compounds represent a group of structurally diverse, small-molecule antagonists of (R, S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptors. Antagonists of AMPA receptors are drug candidates for potential treatment of a number of neurological dis...
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Format: | Article |
Language: | English |
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Elsevier
2015-11-01
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Series: | Acta Pharmaceutica Sinica B |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S221138351500115X |