Anti-bacterial effects of poly-N-acetyl-glucosamine nanofibers in cutaneous wound healing: requirement for Akt1.

Anti-bacterial effects of poly-N-acetyl-glucosamine nanofibers in cutaneous wound healing: requirement for Akt1.

Treatment of cutaneous wounds with poly-N-acetyl-glucosamine nanofibers (sNAG) results in increased kinetics of wound closure in diabetic animal models, which is due in part to increased expression of several cytokines, growth factors, and innate immune activation. Defensins are also important for w...

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Bibliographic Details
Main Authors: Haley Buff Lindner, Aiguo Zhang, Juanita Eldridge, Marina Demcheva, Philip Tsichlis, Arun Seth, John Vournakis, Robin C Muise-Helmericks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084735?pdf=render

Internet

http://europepmc.org/articles/PMC3084735?pdf=render

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