PP2A: The Achilles Heal in MDS with 5q Deletion

PP2A: The Achilles Heal in MDS with 5q Deletion

Myelodysplastic syndromes (MDS) represent a hematologically diverse group of myeloid neoplasms, however, one subtype characterized by an isolated deletion of chromosome 5q (del(5q)) is pathologically and clinically distinct. Patients with del(5q) MDS share biological features that account for the...

Full description

Bibliographic Details
Main Authors: David eSallman, Sheng eWei, Alan eList
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Oncology
Subjects:
p53
MDM2
Lenalidomide
PP2A
myelodysplastic syndrome
RPS14
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00264/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00264/full

Similar Items