Correlation between polymorphism of TYMS gene and toxicity response to treatment with 5-fluoruracil and capecitabine

Correlation between polymorphism of TYMS gene and toxicity response to treatment with 5-fluoruracil and capecitabine

Tumorigenesis is a multiphasic process in which genetic alterations guide the progressive transformation in cancer cells1. In order to evaluate the possible correlation between some gene variants and the risk of the toxicity development onset, two of the polymorphisms of the thymidylate synthase (T...

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Bibliographic Details
Main Authors: Stefano Vitello, Italia Di Liegro, Maria Rita Ricciardi, Chiara Verga, Alessandra Amato, Gabriella Schiera, Carlo Di Liegro, Giuseppe Messina, Patrizia Proia
Format: Article
Language:English
Published: PAGEPress Publications 2020-08-01
Series:European Journal of Translational Myology
Subjects:
Cancer
genetics
thymidylate synthase
polymorphisms
toxicity
Online Access:https://pagepressjournals.org/index.php/bam/article/view/8970

Internet

https://pagepressjournals.org/index.php/bam/article/view/8970

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