Toxin import through the antibiotic efflux channel TolC

Toxin import through the antibiotic efflux channel TolC

Bacteria can secrete diffusible protein toxins that kill competing bacteria. Here, the authors use biochemical, biophysical and structural analyses to show how one of these toxins exploits TolC (a major antibiotic efflux channel) to transport itself across the outer membrane of target cells.

Bibliographic Details
Main Authors: Nicholas G. Housden, Melissa N. Webby, Edward D. Lowe, Tarick J. El-Baba, Renata Kaminska, Christina Redfield, Carol V. Robinson, Colin Kleanthous
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24930-y

Internet

https://doi.org/10.1038/s41467-021-24930-y

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