Induction of circulating T follicular helper cells and regulatory T cells correlating with HIV-1 gp120 variable loop antibodies by a subtype C prophylactic vaccine tested in a Phase I trial in India.

Induction of circulating T follicular helper cells and regulatory T cells correlating with HIV-1 gp120 variable loop antibodies by a subtype C prophylactic vaccine tested in a Phase I trial in India.

A Phase I HIV-1 vaccine trial sponsored by the International AIDS Vaccine Initiative (IAVI) was conducted in India in 2009 to test a subtype C prophylactic vaccine in a prime-boost regimen comprising of a DNA prime (ADVAX) and MVA (TBC-M4) boost. The trial demonstrated that the regimen was safe and...

Full description

Bibliographic Details
Main Authors: Sivasankaran Munusamy Ponnan, Soumya Swaminathan, Kannan Tiruvengadam, Vidyavijayan K K, Narayana Cheedarla, Manohar Nesakumar, Sujitha Kathirvel, Rajat Goyal, Nikhil Singla, Joyeeta Mukherjee, Philip Bergin, Jakub T Kopycinski, Jill Gilmour, Srikanth Prasad Tripathy, Hanna Elizabeth Luke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6114930?pdf=render

Internet

http://europepmc.org/articles/PMC6114930?pdf=render

Similar Items