Endogenous morphine in SH-SY5Y cells and the mouse cerebellum.

Morphine, the principal active agent in opium, is not restricted to plants, but is also present in different animal tissues and cell types, including the mammalian brain. In fact, its biosynthetic pathway has been elucidated in a human neural cell line. These data suggest a role for morphine in brai...

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Main Authors: Arnaud Muller, Elise Glattard, Omar Taleb, Véronique Kemmel, Alexis Laux, Monique Miehe, François Delalande, Guy Roussel, Alain Van Dorsselaer, Marie-Hélène Metz-Boutigue, Dominique Aunis, Yannick Goumon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2265639?pdf=render