STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1

STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1

Signal transducer and activator of transcription 3 (STAT3) is a multifunctional factor that regulates inflammation and immunity. Knowledge of its regulatory mechanisms is very limited. Here, we showed that enterovirus 71 (EV71) infection induced the phosphorylation of STAT3 and the expression of its...

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Bibliographic Details
Main Authors: Huanru Wang, Meng Yuan, Shuaibo Wang, Li Zhang, Rui Zhang, Xue Zou, Xiaohui Wang, Deyan Chen, Zhiwei Wu
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
stat
virus
antiviral response
inflammation
nuclear import
immune regulation
Online Access:https://www.mdpi.com/1422-0067/20/19/4870

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https://www.mdpi.com/1422-0067/20/19/4870

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