Neuroprotective effects of autophagy inhibition on hippocampal glutamate receptor subunits after hypoxia-ischemia-induced brain damage in newborn rats

Neuroprotective effects of autophagy inhibition on hippocampal glutamate receptor subunits after hypoxia-ischemia-induced brain damage in newborn rats

Autophagy has been suggested to participate in the pathology of hypoxic-ischemic brain damage (HIBD). However, its regulatory role in HIBD remains unclear and was thus examined here using a rat model. To induce HIBD, the left common carotid artery was ligated in neonatal rats, and the rats were subj...

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Bibliographic Details
Main Authors: Li-xiao Xu, Xiao-juan Tang, Yuan-yuan Yang, Mei Li, Mei-fang Jin, Po Miao, Xin Ding, Ying Wang, Yan-hong Li, Bin Sun, Xing Feng
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; hypoxic-ischemic brain damage; hypoxia; ischemia; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor subunit; GluR; hippocampus; rapamycin; 3-methyladenine; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=3;spage=417;epage=424;aulast=Xu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=3;spage=417;epage=424;aulast=Xu

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