Astragaloside IV suppresses histamine-induced inflammatory factors and mucin 5 subtype AC overproduction in nasal epithelial cells via regulation of inflammation-related genes

Astragaloside IV suppresses histamine-induced inflammatory factors and mucin 5 subtype AC overproduction in nasal epithelial cells via regulation of inflammation-related genes

Allergic rhinitis (AR) is a symptomatic allergic disease that leads to severe inflammation. Astragaloside IV (AS-IV) is a primary active component of Astragalus membranaceus and exerts immune-regulation and anti-inflammatory effects. However, the pharmacological effect of AS-IV in the nasal epitheli...

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Bibliographic Details
Main Authors: Jie Guo, Shuai Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
antihistamine
nasal mucosa
allergic rhinitis
muc5ac
inflammatory cytokine
rna-seq
Online Access:http://dx.doi.org/10.1080/21655979.2021.1965813

Internet

http://dx.doi.org/10.1080/21655979.2021.1965813

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