Imaging of Neuronal Activity in Awake Mice by Measurements of Flavoprotein Autofluorescence Corrected for Cerebral Blood Flow

Imaging of Neuronal Activity in Awake Mice by Measurements of Flavoprotein Autofluorescence Corrected for Cerebral Blood Flow

Green fluorescence imaging (e.g., flavoprotein autofluorescence imaging, FAI) can be used to measure neuronal activity and oxygen metabolism in living brains without expressing fluorescence proteins. It is useful for understanding the mechanism of various brain functions and their abnormalities in a...

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Bibliographic Details
Main Authors: Manami Takahashi, Takuya Urushihata, Hiroyuki Takuwa, Kazumi Sakata, Yuhei Takado, Eiji Shimizu, Tetsuya Suhara, Makoto Higuchi, Hiroshi Ito
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Neuroscience
Subjects:
flavoprotein autofluorescence imaging
intrinsic optical signal imaging
cerebral blood flow
oxygen metabolism
image correction method for green fluorescent imaging
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00723/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00723/full

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