Synthetic Efforts for Stereo Structure Determination of Cytotoxic Marine Natural Product Pericosines as Metabolites of Periconia sp. from Sea Hare

Synthetic Efforts for Stereo Structure Determination of Cytotoxic Marine Natural Product Pericosines as Metabolites of Periconia sp. from Sea Hare

Pericosines are unique C7 cyclohexenoid metabolites of Periconia byssoides OUPS-N133 fungus that was originally isolated from the sea hare, Aplysia kurodai. Pericosines show significant in vitro cytotoxicity against P388 lymphocytic leukemia cells. Pericosine A, in particular, shows the most potent...

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Bibliographic Details
Main Authors: Masao Arimoto, Hayato Ichikawa, Yoshihide Usami
Format: Article
Language:English
Published: MDPI AG 2008-03-01
Series:International Journal of Molecular Sciences
Subjects:
marine natural product
antitumor
pericosine
structure determination
total synthesis
carbasugar
Online Access:http://www.mdpi.com/1422-0067/9/3/401/

Internet

http://www.mdpi.com/1422-0067/9/3/401/

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