Reporter Replicons for Antiviral Drug Discovery against Positive Single-Stranded RNA Viruses

Reporter Replicons for Antiviral Drug Discovery against Positive Single-Stranded RNA Viruses

Single-stranded positive RNA ((+) ssRNA) viruses include several important human pathogens. Some members are responsible for large outbreaks, such as Zika virus, West Nile virus, SARS-CoV, and SARS-CoV-2, while others are endemic, causing an enormous global health burden. Since vaccines or specific...

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Bibliographic Details
Main Authors: Rafaela S. Fernandes, Marjorie C. L. C. Freire, Renata V. Bueno, Andre S. Godoy, Laura H. V. G. Gil, Glaucius Oliva
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
Key-words: replicon systems
(+) ssRNA viruses
direct-acting antivirals
drug discovery
Online Access:https://www.mdpi.com/1999-4915/12/6/598

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https://www.mdpi.com/1999-4915/12/6/598

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