Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury.

Secondary damage following primary spinal cord injury extends pathology beyond the site of initial trauma, and effective management is imperative for maximizing anatomical and functional recovery. Bisperoxovanadium compounds have proven neuroprotective effects in several central nervous system injur...

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Bibliographic Details
Main Authors: Chandler L Walker, Melissa J Walker, Nai-Kui Liu, Emelie C Risberg, Xiang Gao, Jinhui Chen, Xiao-Ming Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3254642?pdf=render