The gating mechanism in cyclic nucleotide-gated ion channels

Abstract Cyclic nucleotide-gated (CNG) channels mediate transduction in several sensory neurons. These channels use the free energy of CNs’ binding to open the pore, a process referred to as gating. CNG channels belong to the superfamily of voltage-gated channels, where the motion of the α-helix S6...

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Bibliographic Details
Main Authors: Monica Mazzolini, Manuel Arcangeletti, Arin Marchesi, Luisa M. R. Napolitano, Debora Grosa, Sourav Maity, Claudio Anselmi, Vincent Torre
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-18499-0