An Enhanced ELISPOT Assay for Sensitive Detection of Antigen-Specific T Cell Responses to Borrelia burgdorferi

An Enhanced ELISPOT Assay for Sensitive Detection of Antigen-Specific T Cell Responses to Borrelia burgdorferi

Lyme Borreliosis is an infectious disease caused by the spirochete Borrelia burgdorferi that is transmitted through the bite of infected ticks. Both B cell-mediated humoral immunity and T cell immunity develop during natural Borrelia infection. However, compared with humoral immunity, the T cell res...

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Bibliographic Details
Main Authors: Gottfried H. Kellermann, Paul V. Lehmann, Diana R. Roen, Chenggang Jin
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Cells
Subjects:
Borrelia infection
T cells
interferon-γ
ELISPOT
Online Access:http://www.mdpi.com/2073-4409/2/3/607

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