Effect of Lipoxin A4 on Lipopolysaccharide-Induced Endothelial Hyperpermeability

Excessive oxidative stress, decreased antioxidant capacity, and enhanced cellular calcium levels are initial factors that cause endothelial cell (EC) hyperpermeability, which represents a crucial event in the pathogenesis of pre-eclampsia. Lipoxin A4 (LXA4) strongly attenuated lipopolysaccharide (LP...

Full description

Bibliographic Details
Main Authors: Huayan Pang, Pan Yi, Ping Wu, Zhuoya Liu, Zhongjie Liu, Jianming Gong, Hua Hao, Lei Cai, Duyun Ye, Yinping Huang
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2011.98