Immunohistochemical localization of key arachidonic acid metabolism enzymes during fracture healing in mice.

This study investigated the localization of critical enzymes involved in arachidonic acid metabolism during the initial and regenerative phases of mouse femur fracture healing. Previous studies found that loss of cyclooxygenase-2 activity impairs fracture healing while loss of 5-lipoxygenase activit...

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Bibliographic Details
Main Authors: Hsuan-Ni Lin, J Patrick O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3917894?pdf=render