Novel mutation of the NOTCH3 gene in Arabic family with CADASIL

Mutations in the NOTCH3 gene are responsible for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an adult onset hereditary angiopathy leading to ischemic stroke, vascular dementia and psychiatric disorders. All mutation of NOTCH3 described so far...

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Bibliographic Details
Main Author: Saeed Bohlega
Format: Article
Published: MDPI AG 2011-07-01
Series:Neurology International
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